Connective Tissue Proper

 

Cellular Component

Fixed Cells | mesenchyme cells, fibroblasts (active and inactive fibroblasts), myofibroblast, adipose cells (white and brown adipose cells), macrophages, mast cells

Transient Cells | plasma cells, lymphocytes, neutrophils, macrophages

Fibroblasts

White Adipose Cells

Loose Connective Tissue

Found

Filling in spaces of the body

Composition

Soft Ground Substance | GAGs i.e. hyaluronic acid found in synovial fluid and vitreous humor

Firm Ground Substance | GAGs i.e. chondroitin sulphate fond in bone

Proteoglycans | aggrecan found in cartilage and connective tissue proper

Glycoproteins | laminin found in basement membrane

Fibrous Component

Collagen Fibres

Type I | connective tissue proper, bone, dentin, tendons, ligaments, skin

Type II | cartilage

Type III (Reticular Fibres) | blood vessels, lung, spleen, liver, lymph nodes, smooth muscle

Type IV | basement membrane

Type V | associated with Type I

Type VII | secures basement membrane to underlying connective tissue

Elastic Fibres

Found in blood vessels, skin, cartilage, lungs, urinary bladder

Loose Connective Tissue 

Loose Connective Tissue

Dense Connective Tissue

 

Dense Regular Connective Tissue

Collagenous | found in tendons, ligaments, and sheaths binding muscles together

Elastic | found in large blood vessels (i.e. aorta), vertebral column

Dense Irregular Connective Tissue

Found | skin, nerves, spleen, ovary, kidney, and lymph nodes

Dense Regular Collagenous Connective Tissue

Tendon

Dense Regular Elastic Connective Tissue

Aorta

Reticular Tissue

Found

Liver sinusoids, bone marrow, lymph nodes, spleen, smooth muscle, Islets of Langerhans

Composition

Type III collagen, fibroblasts, macrophages, reticular cells

Reticular Tissue

Type III Collagen

Reticular Tissue

Type III Collagen

Reticulin Fibres

Type III Collagen

Specialized Connective Tissue

Cartilage

Cellular Component

Chondroblasts, chondrocytes (located in the lacunae), fibroblast

Perichondrium

Dense irregular fibrous connective tissue with Type I collagen fibres

Types of Cartilage

Hyaline Cartilage | composed of Type II collagen with Type I collagen and found in the trachea

Elastic Cartilage | composed of Type II collagen with Type I collagen and found in the external ear

Fibrous Cartilage | composed of collagen fibre networks and found where ligaments or tendons are attached to joints (i.e. knee joint)

Hyaline Cartilage 

Elastic Cartilage 

Elastic Cartilage

Fibrous Cartilage

Fibrous Cartilage

Kitten or Rabbit Knee Joint