Tissues & Organs
Tissues & Organs
Connective Tissue Proper
Cellular Component
Fixed Cells | mesenchyme cells, fibroblasts (active and inactive fibroblasts), myofibroblast, adipose cells (white and brown adipose cells), macrophages, mast cells
Transient Cells | plasma cells, lymphocytes, neutrophils, macrophages
Loose Connective Tissue
Found
Filling in spaces of the body
Composition
Soft Ground Substance | GAGs i.e. hyaluronic acid found in synovial fluid and vitreous humor
Firm Ground Substance | GAGs i.e. chondroitin sulphate fond in bone
Proteoglycans | aggrecan found in cartilage and connective tissue proper
Glycoproteins | laminin found in basement membrane
Fibrous Component
Collagen Fibres
Type I | connective tissue proper, bone, dentin, tendons, ligaments, skin
Type II | cartilage
Type III (Reticular Fibres) | blood vessels, lung, spleen, liver, lymph nodes, smooth muscle
Type IV | basement membrane
Type V | associated with Type I
Type VII | secures basement membrane to underlying connective tissue
Elastic Fibres
Found in blood vessels, skin, cartilage, lungs, urinary bladder
Dense Connective Tissue
Dense Regular Connective Tissue
Collagenous | found in tendons, ligaments, and sheaths binding muscles together
Elastic | found in large blood vessels (i.e. aorta), vertebral column
Dense Irregular Connective Tissue
Found | skin, nerves, spleen, ovary, kidney, and lymph nodes
Reticular Tissue
Found
Liver sinusoids, bone marrow, lymph nodes, spleen, smooth muscle, Islets of Langerhans
Composition
Type III collagen, fibroblasts, macrophages, reticular cells
Specialized Connective Tissue
Cartilage
Cellular Component
Chondroblasts, chondrocytes (located in the lacunae), fibroblast
Perichondrium
Dense irregular fibrous connective tissue with Type I collagen fibres
Types of Cartilage
Hyaline Cartilage | composed of Type II collagen with Type I collagen and found in the trachea
Elastic Cartilage | composed of Type II collagen with Type I collagen and found in the external ear
Fibrous Cartilage | composed of collagen fibre networks and found where ligaments or tendons are attached to joints (i.e. knee joint)